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［摘 要］ 目的 探讨甲病的临床表现以及可能原因。
方法 观察152例临床诊断无明显原发病因的非真菌性甲异常患者的甲皱微循环、血液流变学、骨密度和血常规等的变化。
结果 152例患者中126例（82.
89%）有明显的甲皱微循环血流速度减慢，109例（71.
71%）有重度红细胞聚集现象； 94例(61.84%)具有明显的骨质疏松或骨密度低下；
19 例(12.50%)血钙浓度下降； 对其中的47例患者进行血液流变学检测发现，33例血粘度增高，
其影响因素如红细胞压积、红细胞变形指数和红细胞聚集指数都存在明显的异常。
结论 甲异常中，微循环和血液粘滞性以及骨密度的变化很明显，临床治疗应针对这些方面进行改善。
［关键词］ 甲；微循环；血液流变学；骨密度
［中图分类号］ R 758.72
［文献标识码］
B
［文章编号］ 1001-7089(2005)02-0095-02
Clinical
Analysis of the Nonfungal Nail Disorders
LIU
Bin，FAN Xueli
(Department
of Dermatology，Xijing Hospital，Fourth
Military Medical University，Xi’an
710032，China)
Abstract:
Objective
To discuss the clinical features and possible causes of
the nonfungal nail disorders.
Methods
By detecting the nailfold
microcirculation，hemorrheology，bone
mineral density，plasma level of mineral elements
and blood routine.152 cases of fungal disease were analyzed.
Results
Among the 152 cases，126
patients showed slow flow of blood；109 showed the
increase of erythrocyte aggregation.94 of them had either low bone mineral
density or osteoporosis. And lower level of blood calcium was observed in 19
patients. The hemorrheology study showed the increase of blood viscosity and
the related index were obviously abnormal.
Conclusion
The causes of nail disease are complicated and many
factors are involved.The improvement of the microvascular dysfunction and
hemorrheology might be helpful in treating the nail disorders with unknown
reasons.
Key
words：
Nail；Microcirculation；Hemorrheology；Bone
mineral density
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