性     病

淋菌性和非淋菌性尿道炎后慢性前列腺炎患者前列腺液中凝固酶阴性葡萄球菌耐药性研究

董汉生1,张万宏1,李刚1,柳朝栋1,刘子龙2,赵敏1,徐萍1,孙超1,李玲1

 

[摘  要]  目的  研究淋菌性和非淋菌性尿道炎后慢性前列腺炎(CP)与凝固酶阴性葡萄球菌(CNS)的关系,探讨CNS耐药性检测对临床的指导意义。

方法  584例淋菌性和非淋菌性尿道炎后CP患者前列腺液(EPS)作病原体培养和药敏试验。

结果  275(47.1%)患者EPS中分离出病原体,其中CNS 105(38.1%),性病病原体25(9.1%);药敏试验显示CNS对临床常用抗生素耐药率较高。

结论  CNS为性病后CP的重要致病菌,CNS检测及药敏试验对性病后CP的临床诊断和治疗具有重要指导意义。

[关键词]  性传播疾病;慢性前列腺炎;凝固酶阴性葡萄球菌;培养;耐药

[中图分类号]  R 711.72      [文献标识码]  B      文章编号]  1001-7089(2005)09-0-0

 Study on the Resistance to Antibiotics of Coagulase Negative Staphylococci in Prostatic Fluid of Chronic Prostatitis Following Gonococcal and Nongonococcal Urethritis

 DONG HanshengZHANG WanhongLI Gang,et al

(Department of VenereologyWuhan Institute of Dermatology and VenereologyWuhan 430016China)

 Abstract:  Objective   To study the relationship between chronic prostatitis following gonococcal and nongonococcal Urethritis and the coagulase negative staphylococci (CNS)and to explore the clinical significance of CNS drug resistance detect.

 Methods   athogen culture and antimicrobial agents sensitivity test were applied to expressed prostatic secretion (EPS) in 548 patients with chronic prostatitis following gonococcal and nongonococcal Urethritis.

 Results   Among 548 patients microbes were found in 226 cases (47.1)of which including 79 cases of CNS-positive (38.1) and 25 cses of STDs pathogenpositive. Sensitivity test results showed that the drug resistance rates of CNS to antibiotics commonly utilized in clinics were high.

 Conclusion   CNS are important pathogens which conduct CP following STD. It is of great significance for CNS detect and sensitivity test to clinical diagnosis and treatment.

 Key words   Sexually transmitted diseaseChronic prostatitisCoagulase negative staphylococcusCultureDrug resistance

 

[通讯作者]  湖北省计划生育委员会资金资助(200103)

[作者单位]  1 武汉市皮肤病防治研究所性学科,湖北 武汉  430031
              2
华中科技大学同济医学院计划生育研究所,湖北 武汉  430030

[作者简介]  董汉生(1954-),湖北武汉人,医学学士,副主任医师,主要从事男性病临床和研究。

 [通讯作者]  刘子龙,E-mail:whzwh1718@hotmail.com

 

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